About TRD

Treatment Resistant Depression is simply an episode of depression that does not respond to typical treatments such as psychotherapy or medications. Studies report that as many as three out of every 10 patients in primary care with depression do not respond to any of the treatment options they’ve tried.*

People experiencing TRD may have tried a variety of treatments or therapies for their depression.  These treatments may include different types of antidepressants, combinations of medications, psychotherapy, or other approaches. No treatment seems to ease their depression.

Forty percent of patients do not respond to the first antidepressant they try. Additionally, one out of every five depressed patients stops taking their antidepressant medication because of side effects.**

* Nemeroff CB. Prevalence and management of treatment-resistant depression. J Clin Psychiatry. 2007;68(suppl 8):17-25.


** AHRQ Pub No. 07-EHC007-2A


Questionnaire:


Please let us know which of the following symptoms you may be experiencing.

 Feeling sad, hopeless, or discouraged Trouble concentrating Feeling restless or irritable Feeling tired or having little energy Struggle to perform daily activities Changes in appetite or weight Feelings of guilt or like a failure Feeling pessimistic about the future None of the Above

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